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ex4  (MedChemExpress)
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( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or <t>Ex4</t> ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.
Ex4, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dagan ex4-400 amplifier  (dagan corp)
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dagan corp dagan ex4-400 amplifier
( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or <t>Ex4</t> ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.
Dagan Ex4 400 Amplifier, supplied by dagan corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ex4  (Bachem)
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Bachem ex4
( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or <t>Ex4</t> ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.
Ex4, supplied by Bachem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
ex4 - by Bioz Stars, 2026-03
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glp-1r agonist ex4  (Tocris)
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Tocris glp-1r agonist ex4
( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or <t>Ex4</t> ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.
Glp 1r Agonist Ex4, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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glp-1r agonist ex4 - by Bioz Stars, 2026-03
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exendin-4 ex4  (ApexBio)
90
ApexBio exendin-4 ex4
( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or <t>Ex4</t> ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.
Exendin 4 Ex4, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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exendin-4 ex4 - by Bioz Stars, 2026-03
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ex4  (Tocris)
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Tocris ex4
( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or <t>Ex4</t> ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.
Ex4, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
ex4 - by Bioz Stars, 2026-03
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exendin-4-peg4-maleimide (ex4-peg4− mal)  (ProteoGenix)
90
ProteoGenix exendin-4-peg4-maleimide (ex4-peg4− mal)
( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or <t>Ex4</t> ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.
Exendin 4 Peg4 Maleimide (Ex4 Peg4− Mal), supplied by ProteoGenix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or Ex4 ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.

Journal: The Journal of Clinical Investigation

Article Title: β Cell Gαs signaling is critical for physiological and pharmacological enhancement of insulin secretion

doi: 10.1172/JCI183741

Figure Lengend Snippet: ( A – D ) Control ( n = 34) or Gnas βcell–/– ( n = 23) mice were treated with PBS, D-Ala2-GIP ( A and B ), or Ex4 ( C and D ) at t = –10 minutes. Mice were then challenged with i.p. glucose (1.5 g/kg) and iAUC presented from t = 0. Insulin secretion in D-Ala2-GIP–challenged ( B , n = 23,14) and Ex4-challenged ( D , n = 21,13) mice are shown at baseline ( t = 0) and 10 minutes after glucose challenge ( t = 10). Data are shown as mean ± SEM, * P < 0.05 as indicated. Data were analyzed by 2-way ANOVA of glycemic curves and insulin levels or 2-tailed Student’s t test of the iAUCs.

Article Snippet: Ex4 was purchased from MedChemExpress.

Techniques: Control